Study in the treatment of patients with
Bipolar Disorder with a Major Depression Episode

Study in the treatment of adults with Major Depression

Study in the treatment of patients with Major Depressive Disorder (MDD)

Bipolar Disorder — also known as manic-depressive illness, is a brain disorder that causes unusual shifts in a person's mood, energy, and ability to function. Different from the normal ups and downs that everyone goes through, the symptoms of bipolar disorder are severe. Bipolar disorder causes dramatic mood swings–from overly "high" and/or irritable to sad and hopeless, and then back again, often with periods of normal mood in between. Severe changes in energy and behavior go along with these changes in mood.

If you are experiencing at least some of the following symptoms, you may be suffering from Bipolar Disorder: Have you had highs and lows, and even been hospitalized for them? Feeling down or sad? Have difficulty making decisions? Feeling hopeless or worthless? Can't sleep or sleeping too much? Can't concentrate? Feel like crying? Have low energy, change in appetite, or increased cravings? Just don't enjoy things the way you used to?

If you are between 18 and 65 years of age, have been feeling this way for at least 2 weeks, and are in general good health, you may qualify to participate in a medication treatment research study.

For More Information, call (202)-994-CARE

Major Depression — Every year, depression afflicts more that 11 million Americans. Clinical depression is more than "the blues," which we all experience now and then. Depression affects both sexes, disrupting relationships and interfering with work and daily activities. The symptoms of depression are similar for both men and women, but they tend to be expressed differently. Depression is usually characterized by sadness, negative thinking, lack of motivation, inability to enjoy things, anxiety, irritability, sleep disturbances (too little or too much), appetite or weight changes, difficulty concentrating as well as feelings of anger or guilt. Other common symptoms of depression include low self-esteem, suicidal thoughts, fatigue, apathy, and sexual problems, including reduced sex drive. Depressed people often feel worthless or hopeless, and may experience physical symptoms as well, including chronic pain. The good news is that clinical depression is a very treatable medical illness.

If you are experiencing at least some of the following symptoms, you may be suffering from Major Depression: Sadness Lack of Motivation Negative Thinking Sleep Problems Appetite or Weight Changes Lack of Concentration Feelings of Anger or Guilt

If you are at least 18 years of age, have been feeling this way for at least 4 weeks, and are in general good health, you may qualify to participate in a medication treatment research study.

For More Information, call (202)-994-CARE

Major Depressive Disorder (MDD) -- is also known as major depression or clinical depression.   Major depression is a medical illness that disrupts a person's mood, behavior, thought processes, and physical health.   In some cases, major depressive disorder is a recurrent, episodic illness. This means that a person who has been depressed once and has recovered is likely to have another episode of depression in the future.   Major depression occurs about twice as often in women as in men and affects about 15% of the population.

If you are experiencing one or more of the following symptoms you may be suffering from Major Depressive Disorder.

• Sadness
• Lack of motivation
• Negative thinking
• Problems falling asleep or getting up in the morning
• Appetite or weight changes
• Lack of concentration
• Feelings of anger or guilt

If you are 18 to 65 years old, are in general good health and have been feeling this way for the past month, you may qualify to participate in a clinical research study for Major Depressive Disorder.

For information about this clinical research study, call (202) 994-2273